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Wolf Reik FRS is a molecular biologist, senior group leader and associate director at the Babraham Institute, professor of Epigenetics at the University of Cambridge and associate faculty at the Sanger Institute. Wolf Reik studies how additional information can be added to the genome through a range of processes collectively called epigenetics. He discovered some of the key epigenetic mechanisms important for mammalian development, physiology, genome reprogramming, and human diseases. His early work led to the discovery that the molecular mechanism of genomic imprinting is based on DNA methylation.〔Reik W, Collick A, Norris ML, Barton SC, Surani MA (1987) Genomic imprinting determines methylation of parental alleles in transgenic mice. ''Nature'' 328, 248-251〕 He uncovered non-coding RNA〔Smits G, Mungall AJ, Griffiths-Jones S, Smith P, Beury D, Matthews L, Rogers J, Pask AJ, Shaw G, VandeBerg JL, McCarrey JR, Renfree MB, Reik W, DunhamI (2008) Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. ''Nature Genetics'' 40, 971-976〕 and chromatin looping〔Murrell A, Heeson S, Reik W (2004) Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. ''Nature genetics'' ==Awards and recognition== Wolf Reik has received many awards, including: * 2011, elected member of the Academia Europaea * 2010, elected Fellow of the Royal Society of London * 2003, elected member of the European Molecular Biology Organisation (EMBO) * 2003 Elected Fellow of the Academy of Medical Sciences * 1994 awarded the Wellcome Prize in Physiology 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Wolf Reik」の詳細全文を読む スポンサード リンク
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